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Fruit Flies May Be Key To Non-Hormonal Birth Control | BabyGaga

Research with fruit files may hold the key to creating non-hormonal birth control, according to a new study. As such, women who have unwanted when taking may have alternatives in the future than the current options provided.

Researchers from the University of Connecticut have been working with fruit flies to provide women with better options when it comes to their . This is because the method in which fruit flies make eggs are surprisingly similar to humans, according to

Further still, mice similarly make eggs as well. As such, if compounds stop both the fruit flies and mice from ovulating, according to the publication, it should work in humans as well.


The study, which was published in the journal, , found that there was a need for research in the field of oral contraceptives for women. This is because Big Pharma does not have a desire at this time to develop non-hormonal oral contraceptives given that others on the market are effective in using hormones to stop ovulation.

As a result, after researchers discovered how only one egg is freed from the follicle every month in fruit flies, they wondered if there was a way to stop them altogether in a manner that did not include hormones.

Many women experience side-effects from taking hormonal oral contraceptives, which range from weight gain, irregular cycles, blood clots, bloating, headaches, mood swings, and more, according to .

That is not where the issues end with taking the contraceptives, however.

According to the , while there are studies that have shown that taking oral contraceptives that contain estrogen and progestin lower the risk of endometrial, colorectal, and , there are increased risks of other cancers. Those cancers include breast and cervical.

To find a way to stop the eggs from being released during a cycle, researchers applied for the Gates Foundation's Grand Challenges Explorations Award in hopes of furthering their research, according to . And seeing the merit in their research, the foundation awarded researchers $100,000.

Researchers tried nearly 1,200 different compounds to stop eggs from being released in fruit flies. If the compounds were successful, the next step was to try the compounds on mice.

There were six that were successful in stopping ovulation in the fruit flies, according to the . Of those six, three were successful in the mice.

Two of the compounds worked without affecting the hormone levels in the mice and one was immediately ruled out for use in humans since it has been proven to affect fertility.

The foundation was impressed with the work that researchers were able to complete with the initial monies provided to them. As such, researchers were awarded an additional $1 million to test further compounds.

They were also awarded money from the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

Now, researchers are working with Calibr at Scripps Ranch in San Diego, according to EurekAlert! With their extensive compound library, the joint effort will continue to see if any further compounds stop ovulation from occurring in fruit flies and mice and prove to be safe for human women to take in the future as well.


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